cytokine

Example:The cytokine storm can be life-threatening as it can cause widespread inflammation and organ damage.

Definition:A rapid, excessive activation of the immune system in response to a pathogen or toxin, such as a virus.

Example:During the treatment of certain cancer patients with immunotherapy, cytokine release syndrome can occur as a side effect.

Definition:A condition characterized by the release of excessive amounts of cytokines, leading to systemic inflammation and adverse effects.

Example:Researchers are developing cytokine therapies to target specific immune pathways in the treatment of rheumatoid arthritis.

Definition:A medical treatment that involves the administration of one or more cytokines to modulate the immune response, often used in the treatment of autoimmune diseases and infectious diseases.

Example:Understanding cytokine imbalance is crucial in managing chronic inflammatory diseases.

Definition:A condition where the normal balance of cytokines is disrupted, leading to an overactive or underactive immune response.

Example:The cytokine network is fundamental in coordinating the immune response to pathogens.

Definition:A complex system of interactions among cytokines that regulate various biological processes, including immune response, inflammation, and tissue repair.

Example:Some patients with psoriasis are treated with cytokine blockade to control the immune overreaction.

Definition:A therapeutic approach to inhibit the action of specific cytokines, often used to reduce inflammation and prevent autoimmune responses.

Example:Cytokine signaling plays a critical role in the activation and regulation of innate and adaptive immunity.

Definition:The process by which cytokines transmit signals to other cells through specific receptors on the cell surface, leading to altered cellular responses.

Example:The interaction between cytokine and its receptor is the first step in initiating a cellular response.

Definition:The binding between a cytokine and its specific receptor on the cell surface, which triggers intracellular signaling pathways.

Example:Cytokine screening can help determine the presence of autoimmune conditions based on elevated cytokine levels.

Definition:A diagnostic test to measure the levels of various cytokines in the blood or tissue, used to identify cytokine-mediated diseases or monitor therapeutic response.

Example:Cytokine mapping is essential for developing targeted therapies and understanding the mechanisms of immune regulation.

Definition:The process of identifying and characterizing the signaling pathways mediated by cytokines, including the identification of target cells and intracellular signaling molecules.